Date: Saturday, August 10, Time: 3:35 - 3:55, Room: 6B
DNA STRUCTURE AND PROTEIN-DNA INTERACTIONS
C.R. Calladine rcb@eng.cam.ac.uk
Session Chair: Stephen K. Burley
Rockefeller University/HHMI
1230 York Avenue
New York NY 10021
Phone: 212 327 8336
Fax: 212 327 8337
burley@rockvax.rockefeller.edu
Program Contact: I. Wilson
Dept. Of Mol. Biology
The Scripps Research Inst. MB 13
10666 N. Torrey Pines Rd.
La Jolla CA 92307
FAX 619 554 6105
wilson@scripps.edu
(E1405) MS04.05.01
Date: Saturday, August 10, Time: 3:35 - 3:55, Room: 6B
DNA STRUCTURE AND PROTEIN-DNA INTERACTIONS
C.R. Calladine
rcb@eng.cam.ac.uk
(D0065) MS04.05.02
Date: Saturday, August 10, Time: 3:55 - 4:15, Room: 6B
LAC REPRESSOR: STRUCTURE AND GENETICS
M. Lewis , M. A. Kercher, G. Chang, N. C. Horton, J. H. Miller, H. C. Pace and P. Lu
lewis@xta01.med.upenn.edu
(E1390) MS04.05.03
Date: Saturday, August 10, Time: 4:15 - 4:35, Room: 6B
MECHANISM OF PYRIMIDINE DIMER EXCISION REPAIR: STRUCTURAL BASIS OF DAMAGED DNA RECOGNITION
K. Morikawa , D.G. Vassylyev, T. Kashiwagi, Y. Mikami, M. Ariyoshi, S. Iwai and E. Ohtsuka
dmitry@xg1.beri.co.jp
(D0134) MS04.05.04
Date: Saturday, August 10, Time: 4:35 - 4:50, Room: 6B
STRUCTURES OF NASCENT DUPLEX DNA BOUND TO A THERMOSTABLE DNA POLYMERASE AT 19 RESOLUTION
Lorena S. Beese , Chen Mao, James R. Kiefer, Stephen B. Long and Jeff Braman
beese@bragg.biochem.duke.edu
(E1410) MS04.05.05
Date: Saturday, August 10, Time: 4:50 - 5:10, Room: 6B
STRUCTURAL STUDIES OF TYPE I DNA TOPOISOMERASES
Alfonso Mondragon , Christopher Lima, Neal Lue, Alexandra Patera and Amit Sharma
a-mondragon@nwu.edu
(E1378) MS04.05.06
Date: Saturday, August 10, Time: 5:10 - 5:30, Room: 6B
THE STRUCTURE OF THE YEAST TELOMERIC PROTEIN RAP1 IN COMPLEX WITH DNA: HOW TELOMERIC DNA SEQUENCES ARE RECOGNISED
D. Rhodes , P. Konig, R. Giraldo and L. Chapman
rhodes@mrc-lmb.cam.ac.uk
(S0137) MS04.05.07
Date: Saturday, August 10, Time: 5:30 - 5:45, Room: 6B
STRUCTURE AND FUCTION OF THE DNA REPAIR ENZYME 3-METHLYADENINE DNA GLYCOSYLASE II
S. Fujii , M. Kato, Y. Tokuno, Y. Nakashima, K. Yasumura, K. Odawara, N. Matsushima, K. Tomita, Yuriko Yamagata, K. Ihara
yuriko@protein.osaka.u.ac.jp
(S0340) MS04.05.08
Date: Saturday, August 10, Time: 5:45 - 6:00, Room: 6B
STRUCTURAL ANALYSIS OF THE TBP/TFIIA/TATA COMPLEX
J. H. Geiger , S. Hahn and P. B. Sigler
geiger@csbarg.med.yale.edu
(S0049) PS04.05.09
Session: I, Board: 156, Room: Not Yet Assigned
STRUCTURE-FUNCTION RELATIONSHIPS IN DNA LIGASE FROM THE BACTERIOPHAGE T7
Stephen R. Ashford , Aidan J. Doherty, Hosahalli S. Subramanya and Dale B. Wigley
steve@biop.ox.ac.uk
(E1100) PS04.05.10
Session: I, Board: 157, Room: Not Yet Assigned
DNA POLYMERASE FIDELITY: A STRUCTURAL ANALYSIS
Merilyn M. Blair , N. Mashhoon, C.R.A. Muchmore, M.F. Goodman and W.F. Anderson
merilyn@xray2.pharm.nwu.edu
(E1430) PS04.05.11
Session: I, Board: 158, Room: Not Yet Assigned
DNA-SPECIFIC BINDING BY HIN AND FIS
Thang Chiu , Reid Johnson and Richard E. Dickerson
thang@satre.mbi.ucla.edu
(E1152) PS04.05.12
Session: I, Board: 159, Room: Not Yet Assigned
REFINED STRUCTURES OF HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH A DOUBLED-STRANDED DNA AND AN ANTIBODY FAB FRAGMENT AT 28 RESOLUTION
Jianping Ding , Kalyan Das, Yu Hsiou, Alfredo Jacobo-molina, Stephen H. Hughes and Edward Arnold
ding@cabm.rutgers.edu
(E1227) PS04.05.13
Session: I, Board: 160, Room: Not Yet Assigned
THE CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF HIV-1 INTEGRASE IN A NEW CRYSTAL FORM
Fred Dyda , Alison B. Hickman, Timothy M. Jenkins, Alan Engelman, Robert Craigie and David R. Davies
dyda@ulti.niddk.nih.gov
(S0109) PS04.05.14
Session: I, Board: 161, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF PU1 ETS DOMAIN-DNA COMPLEX: A NEW PATTERN FOR HELIX-TURN-HELIX RECOGNITION
Kathryn Ely , R. Kodabdapani, F. Pio, C-Z. Ni, G. Piccialli, S. McKercher, M. Klemsz and R. A. Maki
(S0289) PS04.05.15
Session: I, Board: 162, Room: Not Yet Assigned
THE CRYSTAL STRUCTURE OF THE HUMAN PAPILLOMAVIRUS 31 E2 DNA BINDING DOMAIN IN THE ABSENCE OF DNA
V. L. Giranda , X. Kong, D. Egan, F. Lindh, T. Holzman, H. S. Yoon and T. Robbins
giranda@abbott.com
(S0360) PS04.05.16
Session: I, Board: 163, Room: Not Yet Assigned
STRUCTURE OF THE LACTOSE OPERON REPRESSOR AND ITS COMPLEXES WITH DNA AND INDUCER
M. A. Kercher , G. Chang, N. C. Horton, P. Lu, J. H. Miller, H. C. Pace and M. Lewis
kercher@crystal.upenn.edu
(E1428) PS04.05.17
Session: I, Board: 164, Room: Not Yet Assigned
INHIBITION OF HIV-1 REVERSE TRANSCRIPTASE VIA A SUBSTRATE INHIBITOR COMPLEX: STRUCTURAL IMPLICATIONS
Mary L. Kopka , Mark Filipowsky and Richard E. Dickerson
kopka@ewald.mbi.ucla.edu
(D0012) PS04.05.18
Session: I, Board: 165, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF KLENOW-ANALOGOUS FRAGMENT OF THERMUS AQUATICUS DNA POLYMERASE I AT 25 RESOLUTION
Sergey Korolev , Murad Nayal, Wayne M. Barnes, Enrico Di Cera and Gabriel Waksman
korolev@gwiris1.wustl.edu
(S0342) PS04.05.19
Session: I, Board: 166, Room: Not Yet Assigned
STRUCTURAL ANALYSIS OF THE TBP/TFIIB/DNA COMPLEX FROM THE HYPERTHERMOPHILIC ARCHAEA PYROCOCCUS WOESEI
P. Kosa , B. DeDecker, G. Ghosh and P. B. Sigler
pkosa@biomed.med.yale.edu
(E1282) PS04.05.20
Session: I, Board: 167, Room: Not Yet Assigned
CRYSTALLIZATION AND PRELIMINARY CHARACTERIZATION OF A HYPERTHERMOSTABLE ARCHEAL DNA POLYMERASE
Chen Mao , Min Zhou, James R. Kiefer, Robecca Kucera, Maurice Southworth, Francine Perler and Lorena S. Beese
cmao@ewald.biochem.duke.edu
(E1115) PS04.05.21
Session: I, Board: 168, Room: Not Yet Assigned
DNA-BINDING DOMAIN OF OmpR, A DIFFICULT STRUCTURE DETERMINATION
Erik Martinez-Hackert , Helen Berman and Ann Stock
(E0680) PS04.05.22
Session: I, Board: 169, Room: Not Yet Assigned
STRUCTURAL BASIS FOR THE REMOVAL AND EXCLUSION OF URACIL FROM DNA
Clifford D. Mol , Geir Slupphaug, Andrew S. Arvai, John A. Tainer, Bodil Kavli and Hans E. Krokan
cliff@scripps.edu
(E1050) PS04.05.23
Session: I, Board: 170, Room: Not Yet Assigned
DNA POLYMERASE II FROM ESCHERICHIA COLI
C. R. A. Muchmore , M. M. Blair, L. Shuvalova, M. F. Goodman and W. F. Anderson
crmuchmore@xray3.pharm.nwu.edu
(E0745) PS04.05.24
Session: I, Board: 171, Room: Not Yet Assigned
REFINEMENT STRATEGIES FOR PROTEIN-NUCLEIC ACID COMPLEXES
G.N Parkinson , B. Schneider, J. Vojtechovsky, R.H. Ebright and H.M. Berman
parkinson@dnarna.rutgers.edu
(E0737) PS04.05.25
Session: I, Board: 172, Room: Not Yet Assigned
THE BATTLE FOR IRON - CRYSTALLOGRAPHIC STUDIES OF THE IRON DEPENDENT REPRESSOR PROTEINS FROM C DIPHTHERIA AND M TUBERCULOSIS
Ehmke Pohl , Xiayang Qiu, Randall K. Holmes and Wim G.J. Hol
ehmke@gouda.bmsc.washington.edu
(E0927) PS04.05.26
Session: I, Board: 173, Room: Not Yet Assigned
STUDIES TOWARD THE X-RAY CRYSTAL STRUCTURE OF HELICASES
Christopher Putnam and John Tainer
cdputnam@scripps.edu
(E1071) PS04.05.27
Session: I, Board: 174, Room: Not Yet Assigned
PROGRESS IN THE STRUCTURE DETERMINATION OF A HUMAN TOPOISOMERASE I-DNA COMPLEX
Matthew R. Redinbo , Lance Stewart, Ehmke Pohl, Xiayang Qiu, James J. Champoux and Wim G.J. Hol
redinbo@gouda.bmsc.washington.edu
(E0897) PS04.05.28
Session: I, Board: 175, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDIES OF THE ARCHAEAL INTRON ENCODED ENDONUCLEASE I-DMOI
George H. Silva , Jacob Z. Dalgaard, Marlene Belfort and Patrick Van Roey
silva@wadsworth.org
(S0346) PS04.05.29
Session: I, Board: 176, Room: Not Yet Assigned
CRYSTAL STRUCTURAL ANALYSIS OF THREE SURFACE MUTANTS OF THE GENE V PROTEIN OF M13
Shao Yu Su , Yi Gui Gao, Howard Robinson, Hong Zhang, Thomas C. Terwilliger and Andrew H.-J. Wang
(S0050) PS04.05.30
Session: I, Board: 177, Room: Not Yet Assigned
THE THREE DIMENSIONAL STRUCTURE OF AN ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7
Hosahalli S. Subramanya , Aidan J. Doherty, Stephen R. Ashford and Dale Wigley
subs@biop.ox.ac.uk
(E1267) PS04.05.31
Session: I, Board: 178, Room: Not Yet Assigned
X-RAY CRYSTALLOGRAPHIC STUDIES OF A COMPLEX OF MMLV REVERSE TRANSCRIPTASE WITH NUCLEIC ACID
Dunming Sun , Sven Jessen and Millie Georgiadis
dsun@biovax.rutgers.edu
(E1137) PS04.05.32
Session: I, Board: 179, Room: Not Yet Assigned
A HIGH RESOLUTION STRUCTURE OF AN ECORV-DNA COMPLEX
Mark P. Thomas , E. Louise Hancox, Stephen E. Halford and R. Leo Brady
thomasm@bsa.bristol.ac.uk
(S0051) PR04.05.33
CRYSTAL STRUCTURE OF THE DNA GYRASE B PROTEIN FROM B STEAROTHERMOPHILUS
F. T. F. Tsai , H. S. Subramanya, J. A. Brannigan, A. J. Wilkinson, T. Skarznski, O. M. P. Singh, A. J. Wonacott and D. B. Wigley
francis@biop.ox.ac.uk
(S0365) PS04.05.34
Session: I, Board: 181, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF MBP1, A TRANSCRIPTION FACTOR IMPORTANT IN PROGRESSION FROM G1 TO S PHASE
Rui-ming Xu , Christian Koch, Kim Nasmyth and Xiaodong Cheng
xur@cshl.org
(E1431) PS04.05.35
Session: I, Board: 182, Room: Not Yet Assigned
CRYSTALLIZATION OF THE FELINE IMMUNODEFICIENCY VIRUS INTEGRASE PROTEIN
Ann E. Maris , Yoshio Shibagaki, Mary L. Kopka, Thang Chiu, Samson A. Chow and Richard E. Dickerson
maris@ewald.mbi.ucla.edu
(S0821) PS04.05.36
Session: I, Board: 183, Room: Not Yet Assigned
CRYSTALLISATION OF HPV-16 E2 DNA-BINDING DOMAIN APO- AND CO-CRYSTALS
Stephanie Roberts , Hilary Muirhead and Tony Clarke
roberts@bsa.bris.ac.uk
(S0783) PR04.05.37
REPA1, A REPLICATIN CONTROL PROTEIN OF THE REPFIC REPLICON OF PLASMID ENTP307
Simon E.V. Phillips , Haiwei Song, Renata Maas and Mark R. Parsons
sevp@biovax.leeds.ac.uk
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