Date: Friday, August 09, Time: 10:05 - 10:30, Room: 6B
STRUCTURAL BASIS FOR PHOSPHOPEPTIDE RECOGNITION AND CATALYSIS BY PROTEIN PHOSPHATASES
David Barford , Amit Das and Marie-Pierre Egloffdavid@biop.ax.ac.uk
Session Chair: Louise Johnson
Univ Of Oxford
Rex Richards Bldg
South Parks Rd
Oxford UK
Phone: 0865 275365
Fax: 0865 510454
louise@biop.ox.ac.uk
Program Contact: L. Johnson
Univ Of Oxford
Rex Richards Bldg
South Parks Rd
Oxford
UK
FAX 0865 510454
louise@biop.ox.ac.uk
(S0751) MS04.01.01
Date: Friday, August 09, Time: 10:05 - 10:30, Room: 6B
STRUCTURAL BASIS FOR PHOSPHOPEPTIDE RECOGNITION AND CATALYSIS BY PROTEIN PHOSPHATASES
David Barford , Amit Das and Marie-Pierre Egloff
david@biop.ax.ac.uk
(S0686) MS04.01.02
Date: Friday, August 09, Time: 10:30 - 10:55, Room: 6B
MAP KINASES AND THEIR ACTIVATING ENZYMES
Elizabeth Goldsmith
betsy@howie.swmed.edu
(S0270) MS04.01.03
Date: Friday, August 09, Time: 10:55 - 11:20, Room: 6B
ENZYMATIC C5-CYTOSINE METHYLATION OF DNA
Xiaodong Cheng
(E1434) MS04.01.04
Date: Friday, August 09, Time: 11:20 - 11:45, Room: 6B
STRUCTURE AND MECHANISM OF SLT70, A BACTERIAL MURAMIDASE
Bauke Dijkstra (THE NETHERLANDS), Andy-Mark W.H. Thunnissen and Erik van Asselt
bauke@chem.rug.nl
(E0117) MS04.01.05
Date: Friday, August 09, Time: 11:45 - 12:00, Room: 6B
AN EVOLUTIONARY FUSION OF TWO ENZYMES: STRUCTURE OF THE UNIQUE BIFUNCTIONAL ENZYME 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6BISPHOSPHATASE
Charles A. Hasemann , E. Istvan, K. Uyeda and Johann Deisenhofer
hasemann@howie.swmen.edu
(E1029) MS04.01.06
Date: Friday, August 09, Time: 12:00 - 12:15, Room: 6B
STRUCTURE OF URATE OXIDASE OF ASPERGILLUS FLAVUS: AN ORIGINAL FOLD AND A NEW MECHANISM
N. Colloc'h , M. El. Hajji, B. Castro, T. Prang, M. Schiltz, B. Bachet and J. P. Mornon
colloch@lmcp.jussieu.fr
(D0035) MS04.01.07
Date: Friday, August 09, Time: 12:15 - 12:30, Room: 6B
ARGININOSUCCINATE LYASE & II CRYSTALLIN: INTRAGENIC COMPLEMENTATION AND CATALYSIS
P. Lynne Howell , Mary A. Turner, Mona Abu Abed and Rod R. McInnes
(D0021) PS04.01.08
Session: I, Board: 044, Room: Not Yet Assigned
X-RAY STUDIES ON THE STRUCTURE, SPECIFICITY AND MECHANISM OF THE OPINE DEHYDROGENASE ENZYME SUPERFAMILY
S. J. Langridge , K. L. Britton, Y. Asano and D. W. Rice
s.j.langridge1@sheffield.ac.uk
(D0132) PS04.01.09
Session: I, Board: 045, Room: Not Yet Assigned
TYR-LYS BASED CATALYSIS: THE FOUNDATION FOR STRUCTURAL HOMOGY AMONG SHORT-CHAIN DEHYDROGENASE/REDUCTASES
Debashis Ghosh , W.L. Duax, V. Pletnev, B.M. Burkhart and N. Li
ghosh@hwi.buffalo.edu
(E0378) PS04.01.10
Session: I, Board: 046, Room: Not Yet Assigned
GLUCOSE 6-PHOSPHATE DEHYDROGENASE: LINKS BETWEEN STRUCTURE AND DEFICIENCY
Claire E. Naylor , A. K. Basak, S. Gover, P. J. Mason and M. J. Adams
claire@biop.ox.ac.uk
(E0509) PS04.01.11
Session: I, Board: 047, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM LEISHMANIA MEXICANA: MECHANISTIC IMPLICATIONS AND POTENTIAL DRUG BINDING SITES
Hidong Kim , Christophe Verlinde, Alexander Aronov, Micheal Gelb, Piet Herdewijn and Wim Hol
kim@gouda.bmsc.washington.edu
(E0713) PN04.01.12
Date: Not Yet Assigned, Time: Not Yet Assigned, Room: Not Yet Assigned
MOLECULAR REPLACEMENT AT ITS LIMITS? THE STRUCTURE DETERMINATION OF Tcruzi G-GLYDERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, 12 MONOMERS IN THE ASSYMETRIC UNIT AND 41% DATA COMPLETENESS AT 35A RESOLUTION
Beatriz G. Guimaraes , D. H. F. Souza, W. D. P. Jesus and G. Oliva
bia@ifqsc.sc.usp.br
(E0749) PN04.01.13
Date: Not Yet Assigned, Time: Not Yet Assigned, Room: Not Yet Assigned
THE CRYSTAL STRUCTURE OF TCNUZI GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE: IMPLICATIONS FOR THE CATALYTIC MECHANISM AND NEW POTENTIAL TARGET SITES FOR SELECTIVE INHIBITION
G. Oliva , D.H.F. Souza, A.P.U. Araujo and W.D.P. Jesus
oliva@ifzsc.sc.usp.br
(E0761) PS04.01.14
Session: I, Board: 048, Room: Not Yet Assigned
STRUCTURE OF RAT LIVER ISOVALERYL-COA DEHYDROGENASE
Karen Tiffany , Rosemary Paschke, Jerry Vockley and Jung-Ja Kim
ktiffany@post.its.mcw.edu
(E0946) PS04.01.15
Session: I, Board: 049, Room: Not Yet Assigned
ALCOHOL DEHYDROGENASE: MORE STRUCTURES - IMPLICATIONS TO SPECIFICITY AND FUNCTION
S. Ramaswamy , M. El Ahmed, H. Jonvall, B.V. Plapp and H. Eklund
rams@xray.bmc.uu.se
(E1056) PS04.01.16
Session: I, Board: 050, Room: Not Yet Assigned
PURIFICATION AND CRYSTALLIZATION OF RECOMBINANT LACTATE DEHYDROGENASE OF PLASMODIUM FACLCIPARUM
Debasish Chattopadhyay , Dwight Moore, Patrick Campbell, David Bzik, Barabra A. Fox, Lawrence J. DeLucas and Sthanam V. L. Narayana
(E1154) PS04.01.17
Session: I, Board: 051, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDIES OF HOMOSERINE DEHYDROGENASE FOR THE DESIGN OF NOVEL ANTIFUNGAL AGENTS
Byron DeLaBarre , Gerald D. Wright and Albert M. Berghuis
g9226575@mcmail.cis.mcmaster.ca
(E1234) PS04.01.18
Session: I, Board: 052, Room: Not Yet Assigned
THE CRYSTAL STRUCTURE OF CLASS 3 ALDEHYDE DEHYDROGENASE: IMPLICATIONS TO THE CLASS 1 AND 2 ENZYMES
Zhi-Jie Liu , Julie Sun, John Rose, David Hsiao, Wen-Rui Chang, Yong-Je Chung, Ingrid Kuo, John Hempel, Ronald Lindhal and Bi-Cheng Wang
rose@bc14.biochem.uga.edu
(S0285) PS04.01.19
Session: I, Board: 053, Room: Not Yet Assigned
X-RAY STRUCTURE OF INOSINE MONOPHOSPHATE DEHYDROGENASE FROM THE PROTOZOAN PARASITE TRITRICHOMONAS FOETUS
Frank G. Whitby , Hartmut Luecke, John Somoza, Hiro Tsaruta, Jorge Huete-Parez, Cristopher P. Hill, Robert J. Fletterick and Ching Chung Wang
frankw@solitude.med.utah.edu
(S0361) PS04.01.20
Session: I, Board: 054, Room: Not Yet Assigned
STRUCTURAL STUDIES OF RAT LIVER 3A-HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE
Melanie J. Bennett , Brian P. Schlegel, Joseph M. Jez, Trevor M. Penning and Mitchel Lewis
bennett@xtal.med.upenn.edu
(S0484) PS04.01.21
Session: I, Board: 055, Room: Not Yet Assigned
PRELIMINARY CRYSTALLOGRAPHIC ANALSIS OF THE L-PHENYLALANINE DEHYDROGENASE-NAD+ COMPLEX FROM RHODOCOCCUS
Janeen L. Vanhooke , N. M.W. Brunhuber, J.S. Blanchard and H.M. Holden
janeen@enzyme.wisc.edu
(E1394) PS04.01.22
Session: I, Board: 056, Room: Not Yet Assigned
BAD TO SAD: ALCOHOL DEHYDROGENASE AS A "CRYSTALLOGRAPHIC ASSAY" FOR NAD ANALOGS
Barry M. Goldstein , Thomas D. Colby, Krzysztof Pankiewicz and Kyoichi Watanabe
bmg@bphvax.biophysics.rochester.edu
(E1367) PS04.01.23
Session: I, Board: 057, Room: Not Yet Assigned
TWO MUTATIONS IN THE ACTIVE SITE OF ALCOHOL DEHYDROGENASE PERTURB THE CATALYTIC GEOMETRY
Thomas D. Colby , Brian J. Bahnson, Jodie K. Chin, Judith P. Klinman and Barry M. Goldstein
tcol@bphvax.biophysics.rochester.edu
(S0539) PS04.01.24
Session: I, Board: 058, Room: Not Yet Assigned
NATIVE AND COMPLEX CRYSTAL STRUCTURES OF THE FLAVIN ENZYME DIHYDROOROTATE DEHYDROGENASE
Paul Rowland , Finn S. Nielsen, Kaj Frank Jensen and Sine Larsen
paul@xray.ki.ku.dk
(D0091) PS04.01.25
Session: I, Board: 059, Room: Not Yet Assigned
CRYSTALLOGRAPHIC ENZYMOLOGY OF W-AMINO ACID: PYRUVATE AMINOTRANSFERASE
S. Ikemizu , K. Sasaki, N. Watanabe, K. Yonaha, N. Sakabe and K. Sakabe
sakabe@kekvax.kek.jp
(D0095) PS04.01.26
Session: I, Board: 060, Room: Not Yet Assigned
CATALYTIC CONFORMATION OF PSEUDOMONAS 7A GLUTAMINASE-ASPARAGINASE (PGA): CRYSTAL STRUCTURE OF THE PGA-SO42-NH4+ COMPLEX AT 17 RESOLUTION
Clarissa Jakob , M. LaCount, K. Lewinski, J. Roberts and L. Lebioda
cljakob@davidson.edu
(S0059) PS04.01.27
Session: I, Board: 061, Room: Not Yet Assigned
ANALYSES OF DIFFERENT BINDING MODES OF LIGANDS IN THREE TYPES OF CRYSTALS OF L-ASPARAGINASE FROM ECOLI A-1-3KY3598
N. Nandhagopal , M. Hirokawa, N. Tanaka, T. Senda and Y. Mitsui
nandha@voscc.nagaokaut.ac.jp
(S0229) PS04.01.28
Session: I, Board: 062, Room: Not Yet Assigned
KETOACID REDUCTOISOMERASE: FIRST STRUCTURE OF A POTENTIAL HERBICIDE TARGET
Valerie Biou , Eva Pebay-Peyroula, Claudine Cohen-Addad, Renaud Dumas, Dominique Job and Roland Douce
biou@ibs.fr
(E0042) PS04.01.29
Session: I, Board: 063, Room: Not Yet Assigned
CRYSTALLIZATION OF CALPAIN - A CA2+-DEPENDENT CYSTEINE PROTEASE
Zongchao Jia , Qilu Ye, Peter L. Davies A and John S. Elce
jia@crystal.biochem.queensu.ca
(E0373) PS04.01.30
Session: I, Board: 064, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF SUBTILISIN BPN' FOLDED WITHOUT THE PRODOMAIN
Orna Almog , D. Travis Gallagher, Maria Tordova, Joel Hoskins, Phillip Bryan and Gary L. Gilliland
orna@indigo2.carb.nist.gov
(E0494) PS04.01.31
Session: I, Board: 065, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF THE ASPARTIC PROTEINASE FROM RHIZOMUCOR MEIHEI AT 215
Jian Yang , Alexei Teplyakov and J. Wilson Quail
yangj@sask.usask.ca
(E0592) PS04.01.32
Session: I, Board: 066, Room: Not Yet Assigned
CRYSTAL STRUCTURES OF THE GLU18, GLN18, ASP18, AND ASN18 VARIANTS OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STRETOMYCES GRISEUS PROTEINASE B AT VARIOUS PHS
K. Huang . M. Qasim, Wuyuan Lu, Micheal Laskowski and Micheal James
(E0609) PS04.01.33
Session: I, Board: 067, Room: Not Yet Assigned
THE STRUCTURE OF HUMAN CATHEPSIN-L AT 2 RESOLUTION
Richard A. Pauptit , Alec Tucker, Simon Weston and Bob Gordon
pauptit@zeneca-ph.co.uk
(E0715) PS04.01.34
Session: I, Board: 068, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF HUMAN FACTOR XIII BOUND TO YTTERBIUM: PROBING CALCIUM-BINDING
Brian A. Fox , Paul D. Bishop, Ronald E. Stenkamp, David C. Teller and Vivien C. Yee
bafox@u.washington.edu
(E0717) PS04.01.35
Session: I, Board: 069, Room: Not Yet Assigned
THREE DIMENSIONAL STRUCTURE OF A PLANT CARDOON ASPARTIC PROTEINASE
C. Frazao , I. Bento, R. Coelho, J. Costa, C. Faro, P. Vermssimo, E. Pires, J. Cooper, Z. Dauter and K. Wilson
frazao@itqb.unl.pt
(E0776) PS04.01.36
Session: I, Board: 070, Room: Not Yet Assigned
THE 25A CRYSTAL STRUCTURE OF PENICILLIN G ACYLASE FROM A MUTANT FORM OF P RETTGERI
Michael A. McDonough , Herbert E. Klei, Gayle K. Schulte and Judith A. Kelly
mikem@xraysgi.ims.uconn.edu
(E0891) PS04.01.37
Session: I, Board: 071, Room: Not Yet Assigned
THE CRYSTAL STRUCTURE OF A BI-FUNCTIONAL KUNITZ TYPE CYSTEINE PROTEINASE INHIBITOR AT 19 RESOLUTION
Minakshi Ghosh , Michael Mares, Karl Harlos and Colin Blake
mina@biop.ox.ac.uk
(E1097) PR04.01.38
STRUCTURE OF EQUINE INFECTIOUS ANEMIA VIRUS PROTEINASE COMPLEXED WITH AN INHIBITOR
Jukka Kervinen , Alla Gustchina, David Powell, Alexander Zdanov, John Kay and Alexander Wlodawer
kervinen@crysv1.ncifcrf.gov
(S0350) PR04.01.39
CRYSTAL STRUCTURE OF HUMAN PEPSINOGEN
Kathrine S. Bateman , Maia N. Chernaia, Nadya I. Tarasova and Michael N. G. James
kath@zeus.biochem.ualberta.ca
(S0198) PS04.01.40
Session: I, Board: 074, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF HUMAN SALIVARY CRYSTATIN
Narayanan Ramasubbu and Michael J. Levine
subbu@crystall.sdm/buffalo.edu
(E1357) PS04.01.41
Session: I, Board: 075, Room: Not Yet Assigned
CRYSTAL COMPLEXES OF WILD TYPE AND MUTANT CI-2 INHIBITOR WITH SUBTILISIN CARLSBERG: THE STRUCTURAL BASIS FOR BINDING KINETICS AND A HIGH RESOLUTION STUDY
Wojciech R. Rypniewski , Claus Von Der Osten, Torben Halkier and Keith S. Wilson
wojtek@embl-hamburg.de
(E0616) PS04.01.42
Session: I, Board: 076, Room: Not Yet Assigned
STRUCTURE OF A SOLUBLE FORM OF THE KEX1P SERINE CARBOXYPEPTIDASE FROM SACCHAROMYCES CEREVISIAE
Brian H. Shilton , Yunge Li, Daniel Tessier, David Y. Thomas and Miroslaw Cygler
brian.shilton@bri.nrc.ca
(E1175) PS04.01.43
Session: I, Board: 077, Room: Not Yet Assigned
THE MOLECULAR STRUCTURE OF HUMAN CYTOMEGALOVIRUS ASSEMBLIN - A NOVEL SERINE PROTEASE AND AN UNIQUE DRUG TARGET
Huey-Sheng Shieh , William C. Stallings, Ravi G. Kurumbail, Anna M. Stevens, Jina Y. Pak, Eric J. Sturman, Roderick A. Stegeman, Mark O. Palmier, Arthur J. Wittwer and Barry C. Holwerda
hsshie@ccmail.monsanto.com
(S0081) PS04.01.44
Session: I, Board: 078, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF THE COMPLEX OF PORCINE PANCREATIC TRYPSIN WITH KUNITZ-TYPE SOYBEAN TRYPSIN INHIBITOR
Hyun Kyu Song and Se Won Suh
hksong@alliant.snu.ac.kr
(S0388) PS04.01.45
Session: I, Board: 079, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF A NON-PEPSIN-TYPE ACID PROTEINASE, ASPERGILLUS NIGER PROTEINASE A
Hiroshi Sasaki , Atsushi Nakagawa, Tomonari Muramatsu, Kenji Takahashi and Masaru Tanokura
(E0224) PS04.01.46
Session: I, Board: 080, Room: Not Yet Assigned
STRUCTURAL INVESTIGATIONS OF REGULATION IN BACILLUS STEAROTHERMOPHILUS PYRUVATE KINASE
Simon C. Lovell , Daniel Ungar, Abdul H. Mullick and Hilary Muirhead
s.c.lovell@bath.ac.uk
(E0261) PS04.01.47
Session: Not Yet Assigned, Board: Not Yet Assigned, Room: Not Yet Assigned
X-RAY STRUCTURE OF Mn-PHOSPHATE COMPLEX OF YEAST INORGANIC PYROPHOSPHATASE AT 24 RESOLUTION
Boris K. Vainshtein , E. Harutyunyan and I. Kuranova
boris@sucrys.bitnet
(E0304) PN04.01.48
Date: Not Yet Assigned, Time: Not Yet Assigned, Room: Not Yet Assigned
THE X-RAY STRUCTURE OF URIDINE PHOSPHORYLASE FROM E Coli AT 25 A RESOLUTION
A. M. Mikhailov , E. Yu. Morgunova, S. E. Ealick, Ch. Mao, Sh.R. Armstrong, A. S. Mironov and A. A. Komissarov
amm@biostr.crystal.msk.ru
(E0305) PS04.01.49
Session: I, Board: 081, Room: Not Yet Assigned
A GLIMPSE AT AN ENZYME REACTION INTERMEDIATE: THE ATP-MG2+-OXALATE TERNARY COMPLEX OF ESCHERICHIA COLI PHOSPHOENOLPYRUVATE CARBOXYKINASE
Leslie Tari , Allan Matte, Umarani Pugazhenthi, Hughes Goldie and Louis Delbaere
tari@peptide.usask.ca
(E0591) PS04.01.50
Session: I, Board: 082, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF ENZYME IIA OF THE MYCOPLASMA PHOSPHOTRANSFERASE SYSTEM
Kui Huang , Geeta Kapadia, Peng-peng Zhu, Alan Peterofsky and Osnat Herzberg
(E0650) PS04.01.51
Session: I, Board: 083, Room: Not Yet Assigned
15 STRUCTURE OF THE ASP46 HPR MUTANT FROM ESCHERICHIA COLI
Louis T.J. Delbaere , Bruce Waygood, J. Wilson Quail and Scott Napper
napper@sask.usask.ca
(E0704) PR04.01.52
PURIFICATION AND CRYSTALLOGRAPHIC STUDIES OF A D-ALANYL-D-ALANINE CARBOXY-PEPTISDASE FROM B STEAROTHERMOPHILUS
Alexandre P. Kuzin , Janet L. Fronst, Steven L. Condron and Judith A. Kelly
kuzin@uconnvm.uconn.edu
(E1244) PS04.01.53
Session: I, Board: 085, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDIES ON SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI
A.J. Lapthorn , T. Krell, J.E. Coyle and J.R. Coggins
adrian@chem.gla.ac.uk
(S0240) PS04.01.54
Session: I, Board: 086, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS BLOMHOFFII VENOM
Koji Tomoo , M. Doi, T. Ishida, K. Ikeda and Y. Samejima
(S0254) PS04.01.55
Session: I, Board: 087, Room: Not Yet Assigned
THE TRIGONAL AND THE ORTHORHOMBIC FORMS OF THE TRIPLE MUTANT Y52,73F/D99N OF PLA2
K. Sekar , Xin Chen, M.-D Tsai and M. Sundaralingam
sekar@biot.mps.ohio-state.edu
(S0296) PS04.01.56
Session: I, Board: 088, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF FIV dUTP PYROPHOSPHATASE
G. Sridhar Prasad , E. A. Stura, D. E. McRee, C. Hasselkus-Light, G. S. Laco, J.H. Elder and C. D. Stout
prasad@scripps.edu
(S0304) PS04.01.57
Session: I, Board: 089, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF RNASE-FORM I (COMPLEXED WITH NICKEL)
Rama Balakrishnan , N. Rmasubbu, K. I. Varughese and R. Parthasarathy
ramab@acsu.buffalo.edu
(S0403) PS04.01.58
Session: I, Board: 090, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDIES OF ALPHA-TOXIN (PHOSPHOLIPASE C) FROM CLOSTRIDIUM PERFRINGENS
A.K. Basak , J.T. Eaton, D.S. Moss and R.W. Titball
a.basak@cryst.bbk.ac.uk
(S0456) PS04.01.59
Session: I, Board: 091, Room: Not Yet Assigned
LEFT-HANDED B-HELIX PROTEIN UDP-GLUCOSE PYROPHOSPHORYLASE
Masami Kusunoki , Yasuyuki Kitagawa, Hisashi Naitou, Yukiteru Katsube, Yukiyo Sakamoto, Katsuyuki Tanizawa and Toshio Fukui
kusunoki@protein.osaka.u.ac.jp
(S0548) PS04.01.60
Session: I, Board: 092, Room: Not Yet Assigned
CALF SPLEEN PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH AN N(7)-ACYCLOGUANOSINE INHIBITOR
Gertraud Koellner , Marija Luic, Agnieszka Bzowska, David Shugar and Wolfram Saenger
koellner@chemie.fu.berlin.de
(E0405) PS04.01.61
Session: I, Board: 093, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF ISOZYME 4-4 & MOLECULAR MODELING OF ISOZYME 3-4 OF CLASS MU GLUTATHIONE S-TRANSFERASES FROM RAT LIVER
Gaoyi Xiao , Xinhua Ji, Richard Armstrong and Gary L. Gilliland
gaoyi@indigo10.carb.nist.gov
(E0944) PS04.01.62
Session: I, Board: 094, Room: Not Yet Assigned
HIGH RESOLUTION CRYSTAL STRUCTURE OF ORNITHINE AMINOTRANSFERASE COMPLEXED WITH THE NEUROTOXIN GABACULINE
Sapan A. Shah , Betty W. Shen and A.T. Brunger
sapan@laplace.csb.yale.edu
(E0970) PS04.01.63
Session: I, Board: 095, Room: Not Yet Assigned
THE CRYSTAL STRUCTURE OF THE HGXPTRASE FROM THE PROTOZOAN PARASITE T FOETUS
John R. Somoza , Marian Chin, Pamela J. Focia, Ching C. Wang and Robert J. Fletterick
somoza@msg.ucsf.edu
(E1235) PS04.01.64
Session: I, Board: 096, Room: Not Yet Assigned
THE STRUCTURE OF THE DETOXIFICATION ENZYME: GLUTATHIONE S-TRANSFERASE D21 FROM DROSOPHILA MELANOGASTER
Ping-lin Ong , John P. Rose, C.-P. D. Tu and B.C. Wang
ong@bcl7.biochem.uga.edu
(S0038) PS04.01.65
Session: I, Board: 097, Room: Not Yet Assigned
THE HUMAN PI-CLASS GLUTATHIONE S-TRANSFERASE: A TARGET FOR STRUCTURE-BASED DRUG DESIGN
Aaron J. Oakley , Jamie Rossjohn, Mario Lo Bello and Michael W. Parker
s_arrono@eduserv.its.unimelb.edu.au
(S0358) PS04.01.66
Session: I, Board: 098, Room: Not Yet Assigned
PRELIMINARY X-RAY STRUCTURE ANALYSIS OF RAB GERANYLGERANYL TRANSFERASE
Hong Zhang , Miguel C. Seabra and Johann Deisenhofer
zhang@chop.swmen.edu
(E1346) PS04.01.67
Session: I, Board: 099, Room: Not Yet Assigned
HIGH RESOLUTION STRUCTURE OF HUMAN ORNITHINE AMINOTRANSFERASE (OAT) COMPLEXED WITH ALPHA-KETOGLUTARAT: IMPLICATIONS OF THE REACTION MECHANISM
Betty W. Shen , Sapan A. Shah and Axel T. Brunger
bshen@laplace.csb.yale.edu
(E1347) PS04.01.68
Session: I, Board: 100, Room: Not Yet Assigned
THREE DIMENSIONAL STRUCTURE OF HUMAN ORNITHINE AMINOTRANSFERASE: CHARGE DISTRIBUTION AT THE ACTIVE SITE EXPLAINS THE SELECTIVITY FOR W - GROUP OF DIBASIC AMINO ACIDS
Betty W. Shen , Michael Hennig, Erhard Hohenester and Johan N. Jansonius
bshen@laplace.csb.yale.edu
(S0444) PS04.01.69
Session: I, Board: 101, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDY OF BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE FROM ESCHERICHIA COLI
Kengo Okado , Ken Hirotsu, Hideyuki Hayashi and Hiroyuki Kagamiyama
h1852@ocugw.cc.osaka-cu.ac.jp
(S0472) PS04.01.70
Session: I, Board: 102, Room: Not Yet Assigned
STRUCTURE AND FUNCTION OF GLYCINE METHYLTRANSERASE FROM RAT LIVER
Zhuji Fu , Yongbo Hu, Fusao Takusagawa, Kiyoshi Konishi, Yoshimi Takata and Motoji Fujioka
(E0453) PS04.01.71
Session: I, Board: 103, Room: Not Yet Assigned
ENZYME ACTIVITY AT 100C: CITRATE SYNTHASE FROM PYROCOCCUS FURIOSUS
Rupert J. M. Russell , David W. Hough, Michael J. Danson and Garry L. Taylor
r.j.m.russell@bath.ac.uk
(E0790) PS04.01.72
Session: I, Board: 104, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF ASPARAGINE SYNTHETASE FROM ESCHERICHIA COLI
Toru Nakatsu , Hiroaki Kato and Jun'ichi Oda
nakatsu@pclsp2.kuicr.kyoto-u.ac.jp
(E0807) PR04.01.73
INHIBITORS OF GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM AND MYCOBACTERIUM TUBERCULOSIS
Harindarpal Gill , Gunter Harth, Marcus Horwitz and David Eisenberg
hgill@ewald.mbi.ucla.edu
(E1051) PS04.01.74
Session: I, Board: 106, Room: Not Yet Assigned
PRELIMINARY CRYSTALLIZATION AND DIFFRACTION ANALYSIS OF RECOMBINANT PENTALENENE SYNTHASE
Charles A. Lesburg
lesburg@chem.upenn.edu
(E0735) PS04.01.75
Session: I, Board: 107, Room: Not Yet Assigned
STRUCTURES OF ELECTRON TRANSFER FLAVOPROTEIN FROM HUMAN AND PARACOCCUS DENITRIFICANS
David L. Roberts , Frank E Frerman and Jung-ja P. Kim
droberts@post.its.mcw.edu
(E0759) PS04.01.76
Session: I, Board: 108, Room: Not Yet Assigned
STRUCTURE OF THE NATIVE CYSTEINE-SULFENIC ACID REDOX CENTER OF STREPTOCOCCAL NADH PEROXIDASE
Joanne I. Yeh , Al Claiborne and Wim G. J. Hol
joanne@gouda.bmsc.washington.edu
(E0777) PS04.01.77
Session: I, Board: 109, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF RAT LIVER NADPH-CYTOCHROME P-450 REDUCTASE
Ming Wang , David L. Roberts, Rosemary Paschke, Thomas Shea, Bettie Sue S. Masters and Jung-Ja P. Kim
mwang@post.its.mcw.edu
(E0879) PS04.01.78
Session: I, Board: 110, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF COPPER AMINE OXIDASE OF YEAST
Rongbao Li , Longying Chen, Goeffery Boyd, Daiying Cai, Judith Klinman and F. Scott Mathews
rli@iris8.wustl.edu
(E0881) PS04.01.79
Session: I, Board: 111, Room: Not Yet Assigned
THE CRYSTAL STRUCTURE OF A TYPE II DEHYDROQUINASE FROM MYCOBACTERIUM TUBERCULOSIS
D. G. Gourley , J. R. Coggins, A. R. Hawkins and N. W. Isaacs
david@chem.gla.ac.uk
(E1022) PS04.01.80
Session: I, Board: 112, Room: Not Yet Assigned
STRUCTURAL INVESTIGATIONS ON COFACTOR-FREE HALOPEROXIDASES
H. J. Hecht , B. Hofmann, J. Altenbucher and K. H. Van Pe
hjh@gbf-braunschweig.de
(E1089) PS04.01.81
Session: I, Board: 113, Room: Not Yet Assigned
HORSERADISH PEROXIDASE C*: CRYSTAL STRUCTURE WITH AND WITHOUT THE SUBSTRATE: BENZENE HYDROXAMINE ACID (BHA) BOUND IN THE ACTIVE SITE
M. Gajhede , A. Henriksen, D.J. Schuller and A.T. Smith
(E1098) PS04.01.82
Session: I, Board: 114, Room: Not Yet Assigned
ADAPTATION TO EXTREME SALT ENVIRONMENTS: THE STRUCTURE OF DIHYDROFOLATE REDUCTASE FROM HALOFERAX VOLCANII
Ursula Pieper , Geeta Kapadia, Mosh Mevarech and Osnat Herzberg
ursula@indigo6.carb.nist.gov
(S0380) PS04.01.83
Session: I, Board: 115, Room: Not Yet Assigned
X-RAY STRUCTURE ANALYSIS OF ALDEHYDE REDUCTASE FROM A RED YEAST
A. Kita , M. Kataoka, K. Yamamoto, S. Shimizu, K. Kita, T. Hashimoto, H. Yamane and K. Miki
i52743@sakura.kudpc.kyoto-u.ac.jp
(S0389) PS04.01.84
Session: I, Board: 116, Room: Not Yet Assigned
CRYSTALLIZATION AND CRYSTALLOGRAPHY OF THE MAJOR FLAVIN REDUCTASE OF VIRIO FISCHERI
Hideaki Koike , Hiroshi Sasaki, Shuhei Zenno, Kaoru Saigo, Michael E.P. Murphy, Elinor T. Adman and Masaru Tanokura
aa47092@hongo.eccu-tokyo.ac.jp
(S0443) PS04.01.85
Session: I, Board: 117, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDY OF D-AMINO ACID OXDASE
Hisashi Mizutani , Ikuko Miyahara, Ken Hirotsu, Chiaki Setoyama, Yasuzo Nishina, Kiyoshi Shiga and Retsu Miura
(S0476) PS04.01.86
Session: I, Board: 118, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDIES OF LACTATE MONOOXYGENASE (LMO) AND OLD YELLOW ENZYME2(OYE2)
Zhan Deng , Andrew Karplus and Vincent Massey
zdll@cornell.edu
(E1449) PS04.01.87
Session: I, Board: 119, Room: Not Yet Assigned
STRUCTURE OF THE FLAVONZYME D-AMINO ACID OXIDASE
Martino Bolognesi , A. Mattevi, M.A. Vanoni, F. Todone and B. Curti
bolog@ipvgen.unipv.it
(E1350) PS04.01.88
Session: I, Board: 120, Room: Not Yet Assigned
THE CATALYTIC MECHANISM OF SUPEROXIDE DISMUTASE BASED ON CRYSTALLOGRAPHIC STUDIES OF THE REDUCED ENZYME AND INHIBITOR COMPLEXES
Keith S. Wilson , Marta Ferraroni, Pier Luigi Orioli, Wojciech R. Rypniewski and Stefano Mangani
keith@embl-hamburg.de
(S0733) PS04.01.89
Session: II, Board: 072, Room: Not Yet Assigned
THE THREE DIMENSIONAL STRUCTURE OF MOUSE NAD(P)H: QUINONE REDUCTASE EXPRESSED IN E COLI
Mario A. Bianchet , Margarita Faig, Shiuan Chen, Paul Talalay and L. Mario Amzel
bianchet@juliet.med.jhu.edu
(S0749) PS04.01.90
Session: II, Board: 073, Room: Not Yet Assigned
STRUCTURE DETERMINATION OF CHOLESTEROL OXIDASE CONTAINING COVALENTLY BOUND FAD
Kimberley Q. Yue , Nathalie Croteau and Alice Vrielink
kimberley.yue@bri.nrc.ca
(E0808) PS04.01.91
Session: II, Board: 074, Room: Not Yet Assigned
THE STRUCTURE OF N-ACETYLNEURAMINATE LYASE IN COMPLEX WITH INHIBITORS: A NEW SUB-FAMILY OF ALDOLASES
Michael C. Lawrence , J.A.R.G. Barbosa, B.J. Smith, N.E. Hall, P.A. Pilling, H.C. Ooi and S.M. Marcuccio
mike@mel.dbe.csiro.au
(E1439) PS04.01.92
Session: II, Board: 075, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF PECTIN LYASE B DETERMINED BY MOLECULAR REPLACEMENT
Jacqueline Vitali , Brian M. Schick, Harry Kester, Jaap Visser and Frances Jurnak
(E1044) PS04.01.93
Session: II, Board: 076, Room: Not Yet Assigned
ELUCIDATING THE MECHANISM OF TYROSINE PHENOL-LYASE
Alfred Antson , Guy Dodson, Keith Wilson and Tatyana Demidkina
fred@yorvic.york.ac.uk
(E0853) PS04.01.94
Session: II, Board: 077, Room: Not Yet Assigned
PRELIMINARY X-RAY STRUCTURE ANALYSIS OF ACC DEAMINASE
Atsushi Horiuchi , Min Yao, Atsushi Nakagawa, Isao Tanaka and Mamoru Honma
horiuchi@indy.polymer.hokudai.ac.jp
(S0097) PS04.01.95
Session: II, Board: 078, Room: Not Yet Assigned
22 STRUCTURE OF D84E MUTANT OF PORPHOBILINOGEN DEAMINASE
N. C. Picken , R. Lambert, S. Awan, P. M. Jordan and S. P. Wood
ubcgd12@cryst.ddk.ac.uk
(D0075) PS04.01.96
Session: II, Board: 079, Room: Not Yet Assigned
STRUCTURAL STUDY OF SESQUITERPENE CYCLASES
Courtney M. Starks , K. Back, J. Chappell and J. Noel
starks@sbl.salk.edu
(E0025) PS04.01.97
Session: II, Board: 080, Room: Not Yet Assigned
TOWARDS THE STRUCTURE OF HEMAGLUTININNEURAMINIDASE FROM NEWCASTLE DISEASE VIRUS
S. J. Crennell , T. Takimoto, W. G. Laver and G. L. Taylor
S.J. Crennell@bath.ac.uk
(E0041) PS04.01.98
Session: II, Board: 081, Room: Not Yet Assigned
CRYSTAL STRUCTURES OF CYCLOPHILIN A COMPLEXED WITH PROLINE-CONTAINING DIPEPTIDES AND TETRAPEPTIDE
Yingdong Zhao and Hengming Ke
zoo@med.unc.edu
(E0257) PN04.01.99
Date: Not Yet Assigned, Time: Not Yet Assigned, Room: Not Yet Assigned
X-RAY STRUCTURE OF GELONIN AND GELONIN-AMP COMPLEX
M. V. Hosur , Bindu Nair, P. Satyamurthy, S. Misquith, A. Surolia and K. K. Kannan
hosur@magnum.barct1.ernet.in
(E0303) PS04.01.100
Session: II, Board: 082, Room: Not Yet Assigned
STRUCTURE AND INTERACTIONS OF A COMPLEX OF SNAKE VENOM TOXIN AND ACETYLCHOLINESTERASE
Michal Harel , Gerard Kleywegt, Raimond Ravelli, Israel Silman and Joel Sussman
csharel2@weizmann.weizmann.ac.il
(E0323) PS04.01.101
Session: II, Board: 083, Room: Not Yet Assigned
INSIGHTS INTO THE MECHANISM OF RUBISCO
Thomas C. Taylor and Inger Andersson
tom@xray.bmc.uu.se
(E0621) PS04.01.102
Session: II, Board: 084, Room: Not Yet Assigned
FLEXIBLE ASSEMBLY OF PYRUVATE DECARBOXYLASE TETRAMERS EXAMINED BY COMPARISON OF MULTIPLE CRYSTAL FORMS
P. Arjunan , L. Chen, S. Swaminathan, W. Furey, M. Sax, Y. Gao, D. Zhang and F. Jordan
arjun@vms.cis.pitt.edu
(E0659) PS04.01.103
Session: II, Board: 085, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDIES ON SERRALYSINS
Ulrich Baumann
baumann@bio5.chemie.uni-freiburg.de
(E0766) PS04.01.104
Session: II, Board: 086, Room: Not Yet Assigned
STRUCTURE OF AN ANTIBIOTIC DEACTIVATING ENZYME
Lars C. Pedersen and Hazel M. Holden
pedersen@xtall.enzyme.wisc.edu
(E0850) PS04.01.105
Session: II, Board: 087, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF L-2-HALOACID DEHALOGENASE FROM PSEUDOMONAS Sp YL AT 25 RESOLUTION
Yasuo Hata , T. Hisano, T. Fujii, J.-Q. Liu, T. Kurihara, N. Esaki and K. Soda
(E0852) PS04.01.106
Session: II, Board: 088, Room: Not Yet Assigned
CRYSTALLIZATION AND PRELIMINARY X-RAY STRUCTURE ANALYSIS OF D-DOPACHROME TAUTOMERASE
Hiroshi Sugimoto , Atsushi Nakagawa, Isao Tanaka and Jun Nishihira
sugimoto@indy.polymer.hokudai.ac.jp
(E1020) PS04.01.107
Session: II, Board: 089, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PSEUDOMONAS AERUGINOSA EXOTOXIN A COMPLEXED WITH AN NAD ANALOGUE: IMPLICATIONS FOR THE ACTIVATION PROCESS AND FOR ADP-RIVOSYLATION
Mi Li , Fred Dyda, Itai Benhar, Ira Pastan and David Davies
li@vger.niddk.nih.gov
(E1074) PR04.01.108
STRUCTURE AND FUNCTION OF RIBONUCLEOTIDE REDUCTASE R1 PROTEIN
M. Eriksson , S. Ramaswamy, U. Uhlin and H. Eklund
mathias@xray.bmc.uu.se
(E1178) PS04.01.109
Session: II, Board: 091, Room: Not Yet Assigned
A DETAILED STUDY OF THE ACTIVE SITE OF RUBISCO BY X-RAY CRYSTALLOGRAPHY
Anthony P. Duff , T. John Andrews and Paul M.G. Curmi
apd@newt.phys.unsw.edu.au
(E1259) PS04.01.110
Session: II, Board: 092, Room: Not Yet Assigned
THE VERY HIGH RESOLUTION CRYSTAL STRUCTURE OF GLUCOSE OXIDASE FROM PAMAGASAKIENASE 1200 RESIDUES AT 179 RESOLUTION
Jrg Hendle , Hans-Jrgen Hecht, Henryk M. Kalisz and Dietmar Schomburg
jhendle@fred.fhcrc.org
(E1274) PS04.01.111
Session: II, Board: 093, Room: Not Yet Assigned
STRUCTURE AND CRYSTAL PACKING STUDIES OF 4-OXALOCROTONATE TAUTOMERASE
Alexander B. Taylor , Christian P. Whitman and Marvin L. Hackert
taylor@utbc01.cm.utexas.edu
(E1289) PS04.01.112
Session: II, Board: 094, Room: Not Yet Assigned
PRELIMINARY CRYSTALLOGRAPHIC STUDY OF PORMALDEHYDE DISMUTASE
Akihito Yamano , Tsuneyuki Higashi, Hideshi Yanase, Nobuo Kato, Hideaki Moriyama, Nobuo Tanaka and Yukiteru Katsube
yamano@rigaku.co.jp
(S0080) PS04.01.113
Session: II, Board: 095, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF XYLOSE ISOMERASE FROM THERMOPHILIC BACTERIUM THERMUS CALDOPHILUS
Chansoo Chang , Byung Chul Park, Dae-Sil Lee and Se Won Suh
changsoo@sws2.snu.ac.kr
(S0154) PS04.01.114
Session: II, Board: 096, Room: Not Yet Assigned
CRYSTALLOGRAPHIC STUDIES OF THE BIFUNCTIONAL PTERIN-4A-CARBINOLAMINE DEHYDRATASES FROM HUMAN LIVER AND PSEUDOMONAS AERUGINOSA
Dietrich Suck , Ralf Ficner, Uwe H. Sauer and Gunter Stier
suck@embl-heidelberg.de
(S0234) PS04.01.115
Session: II, Board: 097, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF ADP-RIBOSYL CYCLASE
C. D. Stout , G. Sridhar Prasad, E. A. Stura, D. E. McRee, D. G. Levitt and H. C. Lee
dave@scripps.edu
(S0468) PS04.01.116
Session: II, Board: 098, Room: Not Yet Assigned
STRUCTURAL STUDIES OF A BACTERIAL HELICASE
Helga Hoier , Dietmar Roleke, Cornelia Bartsch and Wolfram Saenger
hoier@chemie.fu-berlin.de
(S0717) PS04.01.117
Session: II, Board: 099, Room: Not Yet Assigned
THREE DIMENSIONAL STRUCTURE OF O-ACETYLSERINE SULFHYDRYLASE FROM SALMONELLA TYPHIMURIUM
P. Burkhard , E. Hohenester, G.S.J. Rao, P.F. Cook and J.N. Jansonius
burkhardp@ubaclu.unibas.ch
(E0200) PR04.01.118
CRYSTAL STRUCTURE OF AN ACTIVE FORM OF PORCINE TRYPSIN
A. Johnson , Vasantha Pattabhi and P. V. Sundaram
(E1447) PS04.01.119
Session: II, Board: 100, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF CALCIUM-FREE C-TERMINAL DOMAIN OF SMALL SUBUNIT OF RAT CALPAIN
P. Grochulski , H. Blanchard, Y. Li, J.S.C. Arthur, J.S. Elce, P.L. Davies and M. Cygler
pawel.grochulski@bri.nrc.ca
(S0832) PS04.01.00
Session: Not Yet Assigned, Board: Not Yet Assigned, Room: Not Yet Assigned
CRYSTAL STRUCTURE OF SUBTILISIN DY, A RANDOM MUTANT OF SUBTILISIN CARLSBERG
S. Eschenburg N. Genov Ch. Betzel
susanna@EMBL-hamburg.de
(NONE) PS04.01.00
Session: Not Yet Assigned, Board: Not Yet Assigned, Room: Not Yet Assigned
STRUCTURE OF ENZYME IIB OF THE PEPDEPENDENT CELLOBIOSE SPECIFIC TRANSPORT SYSTEM FROM E. COLI.
ROB L.M. van Montfort (THE NETHERLANDS)
montfort@chem.rug.nl
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